Gout v/s Pseudogout

Feature

Gout

Pseudogout

Cause

Deposition of monosodium
urate (MSU) crystals

Deposition of calcium
pyrophosphate (CPP) crystals

Most common

affected joint

1st Metatarsophalangeal

joint (Podagra)

Knee joint (most common), wrist

Synovial fluid

findings

• Needle-shaped crystals

• Negatively birefringent crystals

• Rhomboid-shaped crystals

• Positively birefringent crystals