Hepatitis B Virus (HBV) Serological Markers

Marker

Indicates

HBsAg

Active infection (acute or chronic)

Anti-HBs

Immunity due to vaccination

or past infection

HBeAg

High viral replication,

more infectivity

Anti-HBe

Low viral replication,

less infectivity

HBcAg

Present inside infected liver cells

(not detected in serum)

Anti-HBc IgM

Recent acute infection

Anti-HBc IgG

Past or chronic infection

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