Feature |
Primary Hyperaldosteronism |
Secondary Hyperaldosteronism |
Definition |
Autonomous overproduction of |
Overproduction of aldosterone due to |
Common |
- Aldosterone producing adenoma - Bilateral adrenal hyperplasia |
- Renal artery stenosis - Congestive heart failure - Cirrhosis - Nephrotic syndrome |
Plasma |
Elevated |
Elevated |
Plasma |
Suppressed (low) |
Elevated (High) |
Aldosterone-to- |
High |
Normal or low |
Potassium |
Decreased (hypokalemia) |
Decreased (hypokalemia) |
Acid-Base |
Metabolic alkalosis |
Metabolic alkalosis |