Biomarker |
Onset |
Peak |
Troponin I |
3-12 hrs |
24 hrs |
Troponin T |
3-12 hrs |
12 hrs - 2 day |
CK-MB |
4-8 hrs |
24 hrs |
Myoglobin |
1-4 hrs |
12 hrs |
Troponin I (cTnI)
Troponin T (cTnT)
- Myoglobin is useful for early diagnosis but is not cardiac-specific (found in skeletal muscle too).
- Troponins (cTnI and cTnT) are the gold-standard biomarkers for MI due to their high sensitivity and specificity.