The Siewert classification is used to classify adenocarcinomas of the gastroesophageal junction (GEJ) based on the anatomical location of the tumor's epicenter relative to the gastroesophageal junction.
|
Type |
Location of Tumor Center |
Origin |
Clinical Notes |
|
Type I |
1–5 cm above GEJ (distal esophagus) |
Arises from Barrett’s esophagus |
Treated like esophageal cancer |
|
Type II |
1 cm above to 2 cm below GEJ (true cardia) |
Cardia carcinoma |
Treated as GEJ cancer |
|
Type III |
2–5 cm below GEJ (subcardial stomach) |
Arises from proximal stomach |
Treated like gastric cancer |
