Apolipoprotein B48 & B100

Feature

Apolipoprotein B48

Apolipoprotein B100

Synthesis
site

Intestines (Enterocytes)

Liver

Length

48% shorter than
Apolipoprotein B100

Full-length
(4,536 amino acids)

Amino acid
Ssequence

Truncated form of
Apolipoprotein B100

Full-length,
longer sequence

RNA Editing

Result of RNA editing
(cytidine to uridine conversion)

No RNA editing,
full-length protein

Major
component

Chylomicron

VLDL, IDL, LDL

Function

Involved in lipid transport
from intestines

Involved in lipid
transport
from liver