Inclusion bodies (Cytopathic effect)

Inclusion bodies

Examples

Intracytoplasmic
inclusion bodies

• Negri bodies— seen in rabies virus (bullet shape)

• Paschen body— seen in variola virus (Small pox)

• Guarnieri bodies— seen in vaccinia virus

• Bollinger bodies— seen in fowlpox virus

• Molluscum bodies (Henderson-Paterson bodies) —
seen in molluscum contagiosum virus (MCV)
(PYQ: INI CET)

• Perinuclear cytoplasmic body— seen
in reovirus (Non-Enveloped, ds-RNA)

Intranuclear
inclusion bodies

Cowdry type A inclusions: (Mnemonic: TAL)

• Torres body— seen in Yellow fever virus (17D vaccine)

• Lipschultz body—seen in Herpes simplex virus (HSV)

Cowdry type B inclusions: (Mnemonic: ABP)

• Poliovirus

• Adenovirus

Intracytoplasmic and
intranuclear
inclusion bodies

• Owl's eye appearance seen in Cytomegalovirus, 
CMV (Owl's eye appearence) 

• Measles virus: Warthin-Finkeldey cell (Multinucleated
giant cells)

Bodies

See in

Michaelis gutmann bodies

(INICET May 2024)

Malakoplakia

(Mnemonic: Dr. FM)

Intranuclear-

• Dutcher bodies

Intracytoplasmic-

• Russell bodies

• Flame cells

• Mott cells

Multiple myeloma
(MM)

Lewy bodies

Parkinson’s disease