Collagen types and their primary locations in the body:
Type of collagen |
Location |
Type 1 (Most abundant & widely distributed) |
Non cartilagenous connective tissue: 1. Bone 2. Tendon 3. Ligament 4. Cornea 5. Skin |
Type 2 |
1. Cartilage 2. Vitreous humor of eye |
Type 3 |
Extensible connective tissue: 1. Lung 2. Blood vessels 3. Skin |
Type 4 |
Basement membrane |
Type 5 |
Often with tissue containing Type I collagen |
Type 6 |
Muscle |
Type 7 |
Dermal epidermal junction |
Feature |
Collagen |
Alport syndrome |
Type IV collagen (Alpha-5 chain) |
Goodpasture syndrome |
Type IV collagen (Alpha-3 chain) |
Osteogenesis imperfecta (Brittle bone disease) |
Type I collagen |