|
Shift |
Right Shift |
Left Shift |
|
Affection for oxygen |
Decreased affinity |
Increased affinity |
|
Hb-oxygen binding |
Oxygen is less tightly bound; more readily released |
Oxygen is more tightly bound; less readily released |
|
Causes |
- Increased CO2 |
- Decreased CO2 |
|
|
- Increased temperature |
- Decreased temperature |
|
|
- Decreased pH (acidosis) |
- Increased pH (alkalosis) |
|
|
- Increased 2,3-BPG |
- Decreased 2,-BPG |
|
Implication |
Enhanced oxygen delivery to tissues |
Reduced oxygen delivery to tissues |