Darrow Yannet diagram





Hypotonic solution

(eg. 0.45% NaCl)

Isotonic solution

(eg. 0.9% NaCl)

Hypertonic solution

(eg. 2% NaCl)

ECF

volume

Increase

Increase 

Increase 

ECF

osmolality

Decrease 

No change

Increase

ICF

volume 

Increase

No change

Decrease

ICF

osmolality 

Decrease 

No change

Increase


Reference: 

1. Guyton & Hall Textbook of Medical Physiology, 2nd edition, P. No. 53 

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