Disorder | Receptor defect | Platelet adhesion | Platelet aggregation |
Glanzmann Thrombasthenia | GP IIb/IIIa defect | Normal adhesion | Impaired aggregation due to defective fibrinogen binding |
Bernard-Soulier Syndrome | GP Ib defect | Impaired adhesion to von Willebrand factor (vWF) | Normal aggregation |
