Lung cancer

Lung cancer is broadly classified into two main types based on size & appearance of the cancer cells under a microscope.

 

1. Non small cell lung cancer (NSCLC)-

- Adenocarcinoma 

- Squamous cell carcinoma 
- Large cell carcinoma 

 

2. Small cell lung cancer (SCLC)-

 

 

Lung cancer

Smoking history 

(Mnemonic: SSS)

Marker

Adenocarcinoma

(Mnemonic: AAA)

 Absent

- NAPSIN A

- TTF 1

Squamous cell carcinoma 

Present 

- p40

- p63

Small cell carcinoma

(Oat cell carcinoma)

Present 

- Synaptophysin

- Chromogranin

- CD57

Large cell carcinoma

Absent

-

 

NOTE: In women & non-smokers adenocarcinoma is most common.

 

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